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姚建铨院士团队在国际TOP期刊Nanoscale上发表最新研究成果

发布时间:2019-12-09  来源:   查看:

近日,由我校特聘院士姚建铨、光电工程学院梁兰菊教授共同指导,光电工程学院闫昕博士和联合培养张璋博士、杨茂生博士在太赫兹生物传感器方面的研究工作取得最新进展,相关成果发表在国际期刊《Nanoscale》(SCI一区,TOP期刊,影响因子6.97)上,闫昕博士与张璋博士为共同第一作者,杨茂生博士为通讯作者。

团队提出并制备了一种基于高阶法诺共振超材料的多模式谐振生物传感器。该传感器通过超材料的四偶极子,八偶极子,十六偶极子法诺共振的频移以及频移的集成化图形探测肺癌细胞的浓度。实验研究得到,随着细胞浓度的增加,法诺共振的频移Δf依次经历增加频移(IFSS),减少频移(DFSS)和重新增加的频移(RIFSS)。通过引入新的介电常数εf,修正了微扰理论以解释Δf中的异常现象。研究结论为太赫兹生物传感器的制备提供了一种新的途径。

上述研究成果得到了国家重点研发计划项目(2017YFA0700202)、国家自然科学基金(61701434, 61735010)、山东省自然科学基金(ZR2017MF005,ZR2018LF001 )、诚信彩票平台市自主创新及成果转化项目基金(2016GH19)、山东省院士专家工作站、山东省光电信息处理与显示重点实验室,教育部重点实验室(天津大学)的资助。

截至目前,姚建铨院士指导诚信彩票平台学院太赫兹科研团队2019年在太赫兹相关领域发表科研论文20篇,其中SCI论文12篇,中科院JCR一区文章3篇,二区文章3篇,ESI高被引论文1篇。


Figure. 1 (a) Schematic diagram of the unit cells for the high order FRMMs, the corresponding structural parameters are: p = 50 ?m, w = 200nm, l = 20 ?m, d = 40 ?m, g = 8 ?m, h =10?m. (b) Simulated transmittance spectra for the x-polarized (black curve) and the y-polarized (red curve) incidence wave. (c) Schematic diagram for the periodic structure. (d) Experimental transmittance spectra for the x-polarized (black dotted curve) and they-polarized (red dotted curve) incidence wave.

Figure. 2 Schematic representation of culturing cells method on higher order FRMMs-based biosensors with A549 cells binding to the metal surface and its equivalent dielectric environment transition mechanism.

Figure. 3 Micrographs of the higher order FRMMs-based biosensor with cell A549 at different concentration changing from 1×104 cel3ls/ml to 5×105cell/ml.

Figure. 4 The measured x-polarized transmittance spectrum of the proposed higher order FRMMs-based biosensors under different cell concentrations (1×104cells/ml, 3×104cells/ml, 5×104cells/ml, 1×105cells/ml, 3×105cells/ml, 5×105cells/ml). (h), (j), (i) The measured x-polarized frequency shift Δf of Qx, Ox and Hx extracted from (a),(b), (c), (d), (e), (f).

Figure. 5 The measured y-polarized transmittance spectrum of the designed higher order higher order FRMMs-based biosensors under different cell concentrations (1×104 cells/ml, 3×104 cells/ml, 5×104 cells/ml, 1×105 cells/ml, 3×105 cells/ml, 5×105 cells/ml) (h), (i) The measured x-polarized frequency shift Δf of Qy and Oy extracted from (a),(b), (c), (d), (e), (f).

Figure. 6 the shapes and distributions of graphics integrated with the Δf for each resonant mode under different cell concentration.


文章链接网址:https://pubs.rsc.org/en/results/journals?Category=journal&AllText=%2010.1039%2FC9NR07777D%20&IncludeReference=false&SelectJournal=True&ArtRefJournalName=Nanoscale%3B&DateRange=false&SelectDate=false&PriceCode=False&OpenAccess=false&JournalName=Nanoscale